{"id":2575,"date":"2025-06-23T11:39:34","date_gmt":"2025-06-23T15:39:34","guid":{"rendered":"https:\/\/medicamentquebec.ca\/?p=2575"},"modified":"2025-11-13T14:52:27","modified_gmt":"2025-11-13T19:52:27","slug":"optimization-and-scale-up-of-rna-therapeutics-through-next-generation-manufacturing","status":"publish","type":"post","link":"https:\/\/medicamentquebec.ca\/index.php\/2025\/06\/23\/optimization-and-scale-up-of-rna-therapeutics-through-next-generation-manufacturing\/?lang=en","title":{"rendered":"Optimization and Scale-Up of RNA Therapeutics Through Next-Generation Manufacturing"},"content":{"rendered":"\r\n

June 23, 2025 – Funded Activities<\/strong><\/p>\r\n

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RNA-based therapies and vaccines represent a versatile and preferred approach to addressing several major public health challenges. However, their production requires RNA to be encapsulated, stabilized, and delivered to the body using nanosuspensions complex structures that must be custom-formulated depending on the targeted organ or cells. This level of customization presents a significant challenge for large-scale production.<\/p>\r\n\r\n\r\n\r\n\r\n\r\n

This project is a collaboration between Professor Xavier Banquy and Davide Brambilla from Universit\u00e9 de Montr\u00e9al and Daria Boffito and Bruno Blais from Polytechnique Montr\u00e9al. The team is receiving $1,240,360 in funding through M\u00e9dicament Qu\u00e9bec, with financial support from the Government of Qu\u00e9bec, to develop an innovative new manufacturing platform for nanosuspensions based on the use of rotating disc mixers (SDM). Optimized by artificial intelligence, this technology will allow for precise control of production parameters and facilitate industrial-scale manufacturing, while complying with strict pharmaceutical standards.<\/p>\r\n\r\n\r\n\r\n

This project goes far beyond technical optimization: it proposes a new standard to make vaccines and biotherapies more accessible on a global scale. It is a structuring initiative supported by Montr\u00e9al-based company RNA Technologies & Therapeutics, German company Lipoid GmbH, and Dutch company Flowid B.V. Thanks to their contribution, the total project value amounts to $1,865,860.<\/p>\r\n\r\n\r\n\r\n

This funding will not only strengthen Qu\u00e9bec\u2019s strategic position in the field of advanced biopharmaceutical production but also respond to a growing need within the industry both in Qu\u00e9bec and internationally.<\/p>\r\n","protected":false},"excerpt":{"rendered":"June 23, 2025 - Funded Activities     RNA-based therapies and vaccines represent a versatile and preferred approach to addressing several major public health challenges....

Lire la suite<\/a><\/p>","protected":false},"author":5,"featured_media":3062,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[],"class_list":["post-2575","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"\nOptimization and Scale-Up of RNA Therapeutics Through Next-Generation Manufacturing - M\u00e9dicament Qu\u00e9bec<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicamentquebec.ca\/index.php\/2025\/06\/23\/optimization-and-scale-up-of-rna-therapeutics-through-next-generation-manufacturing\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Optimization and Scale-Up of RNA Therapeutics Through Next-Generation 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