{"id":2763,"date":"2025-09-18T08:59:21","date_gmt":"2025-09-18T12:59:21","guid":{"rendered":"https:\/\/medicamentquebec.ca\/?p=2763"},"modified":"2025-11-12T13:20:09","modified_gmt":"2025-11-12T18:20:09","slug":"preclinical-tools-and-services-to-decode-b-and-t-cell-repertoires-induced-by-immune-responses-in-non-human-primates","status":"publish","type":"post","link":"https:\/\/medicamentquebec.ca\/index.php\/2025\/09\/18\/preclinical-tools-and-services-to-decode-b-and-t-cell-repertoires-induced-by-immune-responses-in-non-human-primates\/?lang=en","title":{"rendered":"Preclinical tools and services to decode B- and T-cell repertoires induced by immune responses in non-human primates"},"content":{"rendered":"

September 18, 2025 – Funded activities<\/strong><\/p>\n

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As part of its\u00a0Vaccine Technology Innovations<\/em> program, M\u00e9dicament Qu\u00e9bec is supporting four collaborative research initiatives bringing together academia and industry partners. Discover Dr. Estaquier\u2019s project focused on developing preclinical tools and services to decode B- and T-cell repertoires induced by immune responses in non-human primates.<\/strong><\/p>\n

Due to their strong similarity to humans, non-human primates (NHPs) are essential for advancing our understanding of infectious diseases and developing and testing new vaccines and treatments. Interactions between T and B cells within lymphoid organs are critical to generating long-lived memory cells and producing antibodies that can control microbial infections. Gaining deeper insight into these interactions is key to understanding the dynamics of these immune cells, which form the body\u2019s primary defense against pathogens.<\/p>\n

Dr. Estaquier\u2019s team will develop a tool to characterize lymphocyte populations at the single-cell level in order to decipher and monitor T- and B-cell immune responses in NHPs, using single-cell gene analysis approaches.<\/p>\n

This multidisciplinary research activity will involve:<\/p>\n